Congress MP Santokh Singh Chaudhary died after collapsing during the Bharat Jodo Yatra in Jalandhar at the age of 76.

This special issue of the Business and Human Rights Journal explores the intersection of gender, business, and human rights through feminist perspectives. It addresses the systemic discrimination and patriarchal structures that perpetuate gender inequalities in the business and human rights field. Topics include the female sexual and reproductive wellness industry, Indigenous women leaders facing violence in the Americas, the human rights abuses in the garment sector, informal mining and gender-based violence in Colombia, corporate-led women's empowerment initiatives, the juristic personhood of companies, digital ID programs in Kenya, LGBTI discrimination in business, the media's targeting of youth, cross-border surrogacy, sexual harassment in the Kenyan flower industry, and the gendered impacts of corporate human rights due diligence. The issue calls for a reorientation of business practices to embed gender justice and respect for human rights.

The review article discusses the implications of the BDNF gene Val66Met polymorphisms in schizophrenia, highlighting that the Met/Met genotype is associated with higher PANSS positive scores and a history of suicide attempts, while also being linked to worse cognitive function and lower levels of serum BDNF. The Val/Val genotype carriers showed increased BDNF levels correlated with weight gain under Risperidone treatment. The article emphasizes the complexity of factors affecting the BDNF Val66Met polymorphism, including interethnic genetic differences, gender, age, and environmental factors. It suggests that future studies should focus on identifying genetic markers for predicting treatment response in schizophrenia.

The article discusses the integration of feminist perspectives into the field of business and human rights (BHR), highlighting the historical gender-blind approach of BHR frameworks and the need for a shift towards recognizing and addressing unequal power relations. It emphasizes the importance of understanding gender as a multifaceted and intersectional issue, rather than an add-on to corporate responsibility. The article critiques the neoliberal influence on gender integration in BHR and calls for a transformation of patriarchal structures across all themes, actors, and contexts within BHR. It also presents three interconnected themes from the special issue: bodies and embodiment, women's positionality in the marketplace, and borderlessness. The article underscores the need for participatory, inclusive, and transformative political solutions to address gendered human rights harms and advocates for a feminist approach that values diversity and agency.

Parents should focus on encouraging their children to put in their best efforts rather than expecting the best results, especially in situations like important entrance exams. The article argues that staying positive and unchanged in the face of a child's failure teaches them to handle challenges and risks without fear of disappointing their parents. It emphasizes actions over words in teaching children to learn from failures and try again. The article also references studies linking high parental expectations to perfectionism and potential mental health issues in college students.

The phrase 'Best of Luck' can unintentionally pressure children, especially when they are about to take important exams. Parents should act casually and not overreact to exam outcomes, as this can affect a child's ability to treat mistakes as learning opportunities and can hinder their growth. Instead of focusing on performance, parents should expect great efforts and react to exam results in a balanced manner, whether they are good or bad. The article suggests that parents should support their children's preparation and maintain a normal demeanor to foster a healthy environment for their growth.

The article emphasizes the critical role of the rumen microbiome in enhancing cattle production efficiency and reducing environmental impact. It highlights the use of omics technologies to gain insights into metabolic health changes in dairy cattle, which can improve nutritional management. The review underscores the importance of the rumen microbiome in converting low-quality feed into energy, contributing to plant fiber digestion, and influencing ruminant production and health. It also discusses the factors affecting the establishment of the rumen microbiome and the potential for microbial interventions to improve animal health and productivity.

The study investigates the impact of contemporary antiretroviral therapy (cART) on mitochondrial function and iron transport in HIV-infected human microglia and neural-lineage cells. It was found that cART, particularly drugs like bictegravir, significantly impaired mitochondrial bioenergetics and altered cellular iron homeostasis, potentially contributing to cognitive dysfunction in people with HIV. The research suggests that cART may interact with HIV proteins during viral latency, leading to chronic metabolic changes in the brain. The findings highlight the need for further research to understand the metabolic impact of cART and inform new interventions for cognitive impairment in people with HIV.

The study identifies potential therapeutic drug targets against multi-drug resistant Uropathogenic Escherichia coli (UPEC) using a hierarchical in silico technique. The research focuses on Extended-Spectrum Beta-Lactamase (ESBL)-producing UPEC strain NA114, which is resistant to multiple antibiotics. The authors utilized computational tools to analyze proteins for their essentiality, non-homology to the human genome, and gut flora, leading to the identification of seven distinct targets. Two proteins, ECNA114_0085 and ECNA114_1060, were highlighted for their roles in bacterial peptidoglycan biosynthesis and inositol phosphate metabolism, respectively. These findings could aid in designing new drugs to combat infections caused by MDR UPEC.

Life Circle Health Services, a home healthcare enterprise, has received investment from IFCI Venture under the Sage Venture Fund, managed by the Ministry of Social Justice & Empowerment, GOI. This will enable Life Circle to expand its technology-driven services to new cities in India and enhance care for seniors. The company, co-founded by Anant Kumar and Priya Anant, operates in multiple cities and has partnerships for caregiver training. It was incubated at T-Hub and has investment from Groupe SOS. The SAGE Venture Fund invests in startups offering innovative services for the elderly.

Red Bull's opposition to Bullards' trade mark registration for beverages was rejected by the IPO Hearing Officer. Deliveroo announced a £2.5m investment in sustainable packaging to reduce plastic waste. Tesco will proceed with a 'bad faith' claim against Lidl in a trade mark dispute over a yellow circle on a blue square background. Heineken and Virgin Group are engaged in a trade mark dispute over Heineken's non-alcoholic beer 'Desperados Virgin'. Citizen Spritz is set to launch a non-alcoholic drinks range in the UK, tapping into the growing low and no alcohol product market.

A comprehensive transcriptomics analysis of asymptomatic and severe COVID-19 patients identified distinct molecular responses between the two groups. Severe patients showed significant upregulation in genes associated with anti-viral and anti-inflammatory pathways, secondary infections, and cardiac-related issues, while downregulation was observed in genes related to lipid metabolism and adaptive immune response. These findings suggest that severe COVID-19 patients are more susceptible to other health concerns, including non-viral infections, atherosclerosis, autoinflammatory diseases, anemia, and male infertility, providing insights for therapeutic management and disease management.

The NFT market is booming, with a projection to reach $41 billion in 2021. February 2022 sees the launch of several highly anticipated NFT projects, including Coachella NFTs offering lifetime festival passes, The Sandbox's metaverse game land sale, the Tasty Bones collection, Takashi Murakami's Murakami Flowers, and Invisible Friends by Markus Magnusson. These projects span various domains such as art, gaming, and real estate, and are part of the growing trend of incorporating the Metaverse concept. Caution is advised due to potential fraudulent sites in the NFT space.

Taylor Swift's struggle with Big Machine Label Group and Ithaca Holdings LLC over music ownership highlights exploitation in the music industry. Swift's move to re-record her Big Machine catalogue after signing with Universal Music Group aims to reclaim control over her work. The article discusses the broader implications for the industry and other artists, referencing similar experiences of artists like JoJo, Prince, Def Leppard, and TLC. It suggests that Swift's case could inspire industry-wide change and a re-evaluation of recording contracts to better protect artists.

The article is a first-hand report by a new journalist in Singapore, focusing on the riots that took place in Little India in 2013. The riots were sparked by an unfortunate incident involving foreign workers. The report describes the somber mood in the area following the incident, noting that while people were initially shaken, normalcy seemed to return shortly thereafter. The article provides an account of the immediate aftermath of the Little India Riot and its impact on the community.